{"id":1091,"date":"2021-08-25T11:39:28","date_gmt":"2021-08-25T14:39:28","guid":{"rendered":"https:\/\/nuevocindeca.quimica.unlp.edu.ar\/?page_id=1091"},"modified":"2022-04-11T14:23:50","modified_gmt":"2022-04-11T17:23:50","slug":"diseno-de-sistemas-cataliticos-activos-basados-en-enzimas-libres-soportadas-para-aplicaciones-eco-compatibles-en-la-industria-farmaceutica-2","status":"publish","type":"page","link":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/biocatalisis-y-biotransformaciones\/diseno-de-sistemas-cataliticos-activos-basados-en-enzimas-libres-soportadas-para-aplicaciones-eco-compatibles-en-la-industria-farmaceutica-2\/","title":{"rendered":"Dise\u00f1o de sistemas catal\u00edticos activos basados en enzimas libres\/soportadas para aplicaciones eco-compatibles en la industria farmac\u00e9utica"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1091\" class=\"elementor elementor-1091\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c4a616a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c4a616a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4d07ab9\" data-id=\"4d07ab9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-de2b40a elementor-widget elementor-widget-heading\" data-id=\"de2b40a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-large\">Investigadora responsable<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9f481a9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9f481a9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e7aa252\" data-id=\"e7aa252\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-42cb4c4 elementor-widget elementor-widget-image\" data-id=\"42cb4c4\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"198\" height=\"236\" src=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Briand_buena_2021.jpg\" class=\"attachment-large size-large wp-image-2495\" alt=\"\" sizes=\"100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f0bac20 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f0bac20\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/www.conicet.gov.ar\/new_scp\/detalle.php?id=21258&#038;datos_academicos=yes\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Prof. Dra. Laura E. Briand<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fe36d15 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fe36d15\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f30199b\" data-id=\"f30199b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f5b44ff elementor-widget elementor-widget-heading\" data-id=\"f5b44ff\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-large\">Integrantes<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d45a375 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d45a375\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wider\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e8e5db4\" data-id=\"e8e5db4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0364ca1 elementor-widget elementor-widget-image\" data-id=\"0364ca1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"189\" height=\"236\" src=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Carla-Jose_buena_2021-1.jpg\" class=\"attachment-large size-large wp-image-2483\" alt=\"\" sizes=\"100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c364f5b elementor-align-center elementor-widget elementor-widget-button\" data-id=\"c364f5b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md\" href=\"https:\/\/www.conicet.gov.ar\/new_scp\/detalle.php?id=37539&#038;datos_academicos=yes\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Dra. Carla Jos\u00e9<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-cc26f3e\" data-id=\"cc26f3e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-86a2b50 elementor-widget elementor-widget-image\" data-id=\"86a2b50\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"151\" height=\"169\" src=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Victoria-Toledo_buena_2021-e1639838947491.jpg\" class=\"attachment-large size-large wp-image-2491\" alt=\"\" sizes=\"100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1baa2e4 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"1baa2e4\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.conicet.gov.ar\/new_scp\/detalle.php?id=34185&#038;datos_academicos=yes\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Dra. Mar\u00eda Victoria Toledo <\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-b2acf32\" data-id=\"b2acf32\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b89bf27 elementor-widget elementor-widget-image\" data-id=\"b89bf27\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"236\" height=\"236\" src=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Llerena-Suster_buena_2021.jpg\" class=\"attachment-large size-large wp-image-2479\" alt=\"\" srcset=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Llerena-Suster_buena_2021.jpg 236w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Llerena-Suster_buena_2021-150x150.jpg 150w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2021\/11\/Llerena-Suster_buena_2021-100x100.jpg 100w\" sizes=\"100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9cd998 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f9cd998\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.conicet.gov.ar\/new_scp\/detalle.php?id=32935&#038;datos_academicos=yes\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Dr. Carlos R. Llerena Suster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-544c28b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"544c28b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4cf00ab\" data-id=\"4cf00ab\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ee4b85e elementor-widget elementor-widget-text-editor\" data-id=\"ee4b85e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<span style=\"color: #000000;\"><span style=\"font-weight: 400;\">Las investigaciones en este campo tienen como objetivo obtener correlaciones fundamentales entre estructura molecular y actividad catal\u00edtica de lipasas libres e inmovilizadas a los fines de desarrollar biocatalizadores que permitan obtener enanti\u00f3meros de uso farmacol\u00f3gico. En particular, se investiga la resoluci\u00f3n cin\u00e9tica enzim\u00e1tica de (R\/S)-ibuprofeno y (R\/S)-ketoprofeno a trav\u00e9s de la esterificaci\u00f3n enantioselectiva con alcoholes. Se dise\u00f1an, sintetizan y aplican biocatalizadores propios a base de la lipasa B de <\/span><i><span style=\"font-weight: 400;\">Candida antarctica<\/span><\/i><span style=\"font-weight: 400;\"> inmovilizada en nanopart\u00edculas de \u00f3xido de metales de transici\u00f3n (TiO<sub>2<\/sub>, SiO<sub>2<\/sub>, magnetita), soportes org\u00e1nicos (quitosano con y sin funcionalizaci\u00f3n) y pol\u00edmeros. Asimismo, se utilizan y analizan biocatalizadores comerciales.\u00a0<\/span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0253b5b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0253b5b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-62ef031\" data-id=\"62ef031\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2e782c4 elementor-widget elementor-widget-text-editor\" data-id=\"2e782c4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2><span style=\"font-weight: bold; color: #005f61;\">Publicaciones<\/span><\/h2><p><span style=\"color: #000000;\">\u201c<\/span><span style=\"color: #000000; font-size: 1rem;\">Isolation of ibuprofen enantiomers and racemic esters through electrodialysis\u201d Carla Jos\u00e9, Laura E. Briand, Nicol\u00e1s Michlig, Mar\u00eda R. Repetti, Carla Benedetich, Laura M. Cornaglia, Mar\u00eda L. Bosko. Journal of Membrane Science 618 (2021) 118714.<\/span><\/p><p><span style=\"color: #000000;\">\u201cNovozym 435: The perfect lipase immobilized biocatalyst?\u201d, C. Ortiz, M.L. Ferreira, O. Barbosa, J.C.S. dos Santos, R.F. Rodrigues, A. Berenguer-Murcia, L. E. Briand, R. Fern\u00e1ndez-Lafuente,\u00a0<i>Catal. Sci. Technol<\/i>. 9 (2019) 2380-2420.<\/span><\/p><p><span style=\"color: #000000;\">\u201cInfluence of water on enzymatic esterification of racemic ketoprofen with ethanol in a solvent-free system\u201d, Mar\u00eda V. Toledo, Carlos R. Llerena Suster, Claudia Ruscitti, Sebasti\u00e1n E. Collins, Laura E. Briand. Topics Catal. 62 (2019) 968-976.<\/span><\/p><p><span style=\"color: #000000;\">\u00a0\u201cInfluence of the nature of the support and method of immobilization in the catalytic performance of CALB\u201d. Carla Jos\u00e9, Mar\u00eda V. Toledo, Paula Nicol\u00e1s, Ver\u00f3nica Lasalle, Mar\u00eda L. Ferreira, Laura E. Briand. Catal Sci Technol 8 (2018) 3513-3526.\u00a0\u00a0\u00a0<\/span><\/p><p><span style=\"color: #000000;\">\u201cMolecular recognition of an acyl-enzyme intermediate on the lipase B from <em>Candida antarctica<\/em>\u201d. Mar\u00eda V. Toledo, Carlos R. Llerena Suster, Mar\u00eda L. Ferreira, Sebasti\u00e1n E. Collins, Laura E. Briand. Catal Sci Technol 7 (2017) 1953-1964.\u00a0<\/span><\/p><p><span style=\"color: #000000;\">\u201cLipase B of <em>Candida antarctica<\/em> Co-adsorbed with Polyols onto TiO<sub>2<\/sub> Nanoparticles for Improved Biocatalytic Performance\u201d Carlos R. Llerena Suster, Mar\u00eda V. Toledo, Antonela Fittipaldi, Susana R. Morcelle, Laura E. Briand. J. Chem. Technol Biotechnol 92 (2017) 2870-2880.<\/span><\/p><p><span style=\"color: #000000;\">\u201cTowards a green enantiomeric esterification of R\/S-ketoprofen: a theoretical and experimental investigation\u201d. Mar\u00eda V. Toledo, Carla Jos\u00e9, Sebasti\u00e1n E. Collins, Mar\u00eda L. Ferreira, Laura E. Briand. J. Mol. Catal. B: Enzym. 118 (2015) 52-61.\u00a0<\/span><\/p><p><span style=\"color: #000000;\">\u201cInvestigation of the causes of deactivation-degradation of the commercial biocatalyst Novozym\u00ae 435 in ethanol and ethanol-aqueous media\u201d Carla Jos\u00e9, Rita D. Bonetto, Luis A. Gambaro, Mar\u00eda d P. Guauque, Mar\u00eda L. Foresti, Mar\u00eda L. Ferreira, Laura E. Briand. J. Mol. Catal. B: Enzym. 71 (2011) 95-107.<\/span><\/p><p><span style=\"color: #000000;\">\u201cAnalytical characterization and purification of a commercial. Extract of enzymes: a case study\u201d Carlos R. Llerena Suster, Laura E. Briand, Susana R. Morcelle. Colloids<\/span> <span style=\"color: #000000;\">Surf. B-Biointerfaces 121 (2014) 11-20.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ae80f4e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ae80f4e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-869da60\" data-id=\"869da60\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-41d9e8d elementor-widget elementor-widget-image\" data-id=\"41d9e8d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"281\" src=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249-300x281.jpg\" class=\"attachment-medium size-medium wp-image-5473\" alt=\"\" srcset=\"https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249-300x281.jpg 300w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249-1024x960.jpg 1024w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249-768x720.jpg 768w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249-1536x1440.jpg 1536w, https:\/\/cindeca.quimica.unlp.edu.ar\/wp-content\/uploads\/2022\/04\/20220316_172249.jpg 1800w\" sizes=\"100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">XXII Congreso Argentino de Cat\u00e1lisis, Marzo 2022<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Investigadora responsable Prof. Dra. Laura E. Briand Integrantes Dra. Carla Jos\u00e9 Dra. Mar\u00eda Victoria Toledo Dr. Carlos R. Llerena Suster Las investigaciones en este campo tienen como objetivo obtener correlaciones fundamentales entre estructura molecular y actividad catal\u00edtica de lipasas libres e inmovilizadas a los fines de desarrollar biocatalizadores que permitan obtener enanti\u00f3meros de uso farmacol\u00f3gico. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/biocatalisis-y-biotransformaciones\/diseno-de-sistemas-cataliticos-activos-basados-en-enzimas-libres-soportadas-para-aplicaciones-eco-compatibles-en-la-industria-farmaceutica-2\/\" class=\"more-link\">Segu\u00ed leyendo<span class=\"screen-reader-text\"> &#8220;Dise\u00f1o de sistemas catal\u00edticos activos basados en enzimas libres\/soportadas para aplicaciones eco-compatibles en la industria farmac\u00e9utica&#8221;<\/span><\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"parent":941,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/pages\/1091"}],"collection":[{"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/comments?post=1091"}],"version-history":[{"count":139,"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/pages\/1091\/revisions"}],"predecessor-version":[{"id":5488,"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/pages\/1091\/revisions\/5488"}],"up":[{"embeddable":true,"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/pages\/941"}],"wp:attachment":[{"href":"https:\/\/cindeca.quimica.unlp.edu.ar\/index.php\/wp-json\/wp\/v2\/media?parent=1091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}